Description

3β-[(Dibutylaminoacetyl)Oxy]-5,14-Dihydroxy-19-Oxo-5β-Card-20(22)-Enolide is a high-purity, semi-synthetic cardiac glycoside derivative, representing a key intermediate in advanced pharmaceutical research and development. Its value lies in its specific structural modifications, which are critical for studying structure-activity relationships and developing novel therapeutic agents targeting cardiovascular functions. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those focused on cardiology and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel cardiac glycosides and related cardiocative compounds.
• Medicinal Chemistry Research: Used in R&D for studying the structure-activity relationship (SAR) of cardenolide derivatives to optimize potency and selectivity.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Studies: Utilized in in-vitro and ex-vivo studies to investigate the mechanism of action on sodium-potassium ATPase (Na⁺/K⁺-ATPase) pumps.
• Preclinical Development: Acts as a key starting material for the preparation of potential drug candidates in early-stage discovery pipelines.

Basic Information

Item	Details
Product Name	3β-[(Dibutylaminoacetyl)Oxy]-5,14-Dihydroxy-19-Oxo-5β-Card-20(22)-Enolide
CAS No.	64011-27-4
Molecular Formula	C₃₂H₄₉NO₈
Molecular Weight	575.74 g/mol
Synonyms	3β-[(Dibutylaminoacetyl)oxy]-5,14-dihydroxy-19-oxo-5β-card-20(22)-enolide; 3β-[(Dibutylaminoacetyl)oxy]-5,14-dihydroxy-19-oxo-5β,20(22)-cardenolide; 3β-[(Dibutylaminoacetyl)oxy]-5,14-dihydroxy-19-oxocard-20(22)-enolide; Dibutylaminoacetyl Gitoxigenin; Acylated Cardenolide Derivative; Cardiac Glycoside Intermediate; 64011-27-4
EINECS	Contact for details

Quality Control

Our 3β-[(Dibutylaminoacetyl)Oxy]-5,14-Dihydroxy-19-Oxo-5β-Card-20(22)-Enolide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, NMR, and MS. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and desiccated to maintain stability and purity. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.