Description

5-(Furan-2-Ylmethylene)-1,3-Dimethylpyrimidine-2,4,6(1H,3H,5H)-Trione is a specialized heterocyclic compound featuring a furan-methylene-pyrimidinetrione core structure, serving as a high-value chemical intermediate and pharmacophore building block. This compound is critical for research and development in advanced organic synthesis, where its unique fused-ring system enables the construction of complex molecular architectures. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system and anti-inflammatory pathways.
• Agrochemical Research: Building block for developing new generation herbicides and fungicides with specific mode-of-action.
• Material Science: Used in the research of organic semiconductors and photoactive polymers due to its conjugated system.
• Academic & Industrial R&D: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Synthesis: Intermediate for producing specialized dyes, pigments, and complex organic molecules.

Basic Information

Product Name	5-(Furan-2-Ylmethylene)-1,3-Dimethylpyrimidine-2,4,6(1H,3H,5H)-Trione
CAS No.	63987-50-8
Molecular Formula	C11H10N2O4
Molecular Weight	234.21 g/mol
Synonyms	5-(2-Furanylmethylene)-1,3-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione; 1,3-Dimethyl-5-(furan-2-ylmethylene)barbituric acid; 5-(Furan-2-ylmethylene)-1,3-dimethylbarbituric acid; Furan-2-ylmethylene dimethyl barbiturate; 5-(2-Furylmethylene)-1,3-dimethylbarbituric acid; DMFA (context-specific abbreviation); Knoevenagel adduct of 1,3-dimethylbarbituric acid and furfural
EINECS	Contact for details

Quality Control

Our production of 5-(Furan-2-Ylmethylene)-1,3-Dimethylpyrimidine-2,4,6(1H,3H,5H)-Trione adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and industrial use. Quality is verified through advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.