Description

2-Amino-5-Iodoacetamidovaleric Acid is a specialized amino acid derivative featuring a reactive iodoacetamide group. This compound matters as a key building block and bioconjugation reagent in advanced pharmaceutical and biochemical research, enabling the site-specific modification of proteins and peptides. It is primarily needed by researchers and manufacturers in the fields of drug discovery, proteomics, and the development of antibody-drug conjugates (ADCs) and other targeted therapeutics.

Application

• Bioconjugation Reagent: For the site-specific labeling and modification of cysteine residues in proteins and peptides.
• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in oncology research.
• Antibody-Drug Conjugate (ADC) Development: Used to create stable, cleavable linkers for attaching cytotoxic payloads to monoclonal antibodies.
• Proteomics Research: As a tool compound for studying protein structure, function, and interactions.
• Peptide Synthesis: Incorporation into custom peptide sequences to introduce reactive handles or spectroscopic probes.
• Diagnostic Agent Development: For creating labeled probes and contrast agents used in medical imaging and assays.

Basic Information

Product Name	2-Amino-5-Iodoacetamidovaleric Acid
CAS No.	63984-35-0
Molecular Formula	C7H13IN2O3
Molecular Weight	300.10 g/mol
Synonyms	5-Iodoacetamido-2-aminopentanoic Acid; N2-(Iodoacetyl)-L-ornithine; Iodoacetamido-ornithine; L-Ornithine, N5-(iodoacetyl)-; 2-Amino-5-(2-iodoacetamido)pentanoic Acid; Nδ-Iodoacetylornithine; (S)-2-Amino-5-(2-iodoacetamido)pentanoic Acid
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Iodoacetamidovaleric Acid is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each lot undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.