Description

5-Bromo-2,4,6-Trichloropyrimidine is a versatile halogenated pyrimidine building block essential for advanced organic synthesis. Its multi-functional halogen sites enable precise, sequential substitution reactions, making it a critical intermediate for creating complex heterocyclic systems. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of nucleoside analogs, kinase inhibitors, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a precursor for functionalized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: A valuable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Nucleophilic Aromatic Substitution: The chlorine and bromine atoms are selectively displaceable, allowing for stepwise functionalization.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	5-Bromo-2,4,6-Trichloropyrimidine
CAS No.	63931-21-5
Molecular Formula	C4BrCl3N2
Molecular Weight	276.31 g/mol
Synonyms	2,4,6-Trichloro-5-bromopyrimidine; 5-Bromo-2,4,6-trichloro-1,3-diazine; Pyrimidine, 5-bromo-2,4,6-trichloro-; 5-Bromotrichloropyrimidine; 2,4,6-Trichloro-5-bromo-1,3-diazine; BTCP
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,4,6-Trichloropyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.