Description

2-Fluoro-5-Methylphenol is a versatile fluorinated phenolic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a methyl group on the phenol ring, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorine into target molecules to modulate their biological activity, stability, and physicochemical characteristics.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated aromatic systems to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atom can improve lipophilicity and target binding.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers, including polycarbonates and epoxy resins, to impart specific thermal or chemical resistance.
• Organic Electronics: Utilized in the development of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research: Employed in academic and industrial R&D for method development and exploring new fluorination chemistry.

Basic Information

Product Name	2-Fluoro-5-Methylphenol
CAS No.	63762-79-8
Molecular Formula	C7H7FO
Molecular Weight	126.13 g/mol
Synonyms	5-Methyl-2-fluorophenol; 2-Fluoro-5-methylphenol; 2-Fluoro-p-cresol; 5-Methyl-2-fluorophenol; 2-Fluoro-5-hydroxytoluene; o-Fluoro-p-cresol; 1-Fluoro-2-hydroxy-4-methylbenzene
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Methylphenol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including GC, HPLC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	40 - 44 °C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.