Description

2-Amino-4-Methyl-5-Iodo-6-Pyrimidinethiol is a halogenated pyrimidine derivative that serves as a versatile heterocyclic building block. This compound is valued for its unique molecular structure, which combines a reactive thiol group with iodine and amino functionalities, enabling its use in advanced synthetic chemistry. It is primarily sought by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of potential antiviral, anticancer, or antimicrobial agents.
• Agrochemical Synthesis: Used in creating novel pesticides, herbicides, or fungicides where the pyrimidine core is a critical bioactive component.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitutions due to the reactive iodine and thiol groups.
• Ligand Precursor: Can be utilized to develop novel ligands for catalysis or metal-organic frameworks (MOFs).
• Material Science Research: Investigated for the synthesis of specialized organic electronic materials or dyes.
• Biochemical Research: May serve as a substrate or inhibitor in enzymatic studies due to its structural similarity to natural heterocycles.

Basic Information

Product Name	2-Amino-4-Methyl-5-Iodo-6-Pyrimidinethiol
CAS No.	63732-01-4
Molecular Formula	C5H6IN3S
Molecular Weight	267.09 g/mol
Synonyms	5-Iodo-2-amino-4-methyl-6-pyrimidinethiol; 2-Amino-4-methyl-5-iodopyrimidine-6-thiol; 4-Methyl-5-iodo-2,6-diaminopyrimidine (tautomer); 5-Iodo-4-methyl-2-pyrimidinamine-6-thiol; 6-Mercapto-5-iodo-4-methylpyrimidin-2-amine; AI4MPT; 63732-01-4
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Methyl-5-Iodo-6-Pyrimidinethiol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support custom synthesis and can tailor purity grades to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.