Description

4-Chloro-6-(4-Methylpiperazino)-5-Methylthio-2-Piperidinopyrimidine is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for the synthesis of specialized active pharmaceutical ingredients (APIs) and serves as a key building block in medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly in therapeutic areas requiring sophisticated heterocyclic scaffolds.
• Medicinal Chemistry Research: Serves as a versatile building block for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• API Synthesis: Used in the multi-step synthesis of target active pharmaceutical ingredients, especially those containing piperazine and pyrimidine pharmacophores.
• Chemical Biology Probes: Employed in the development of specialized probes and inhibitors for studying biological pathways and enzyme functions.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	4-Chloro-6-(4-Methylpiperazino)-5-Methylthio-2-Piperidinopyrimidine
CAS No.	63731-99-7
Molecular Formula	C15H24ClN5S
Molecular Weight	341.90 g/mol
Synonyms	4-Chloro-6-(4-methyl-1-piperazinyl)-5-(methylthio)-2-(1-piperidinyl)pyrimidine; 2-Piperidino-4-chloro-6-(4-methylpiperazino)-5-methylthiopyrimidine; 5-Methylthio-4-chloro-6-(4-methylpiperazino)-2-piperidinopyrimidine; 4-Chloro-6-(4-methylpiperazinyl)-5-methylthio-2-piperidinopyrimidine; 63731-99-7; 4-Chloro-6-(4-methylpiperazino)-5-methylmercapto-2-piperidinopyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-(4-Methylpiperazino)-5-Methylthio-2-Piperidinopyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.