Description

4-Chloro-2-Diethylamino-6-(4-Methylpiperazino)-5-(Methylthio)Pyrimidine is a high-value, multi-functional pyrimidine derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its complex structure, featuring chloro, diethylamino, methylpiperazino, and methylthio substituents, makes it a versatile building block for constructing pharmacologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel compounds with targeted biological activity. We supply this intermediate with a focus on high purity and batch-to-batch consistency to support your most demanding synthesis projects.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic research.
• Agrochemical Research: Used as a building block for developing new pesticides, herbicides, and fungicides with specific modes of action.
• Chemical Biology & Proteomics: Employed in the design and synthesis of chemical probes and inhibitors for studying enzyme function and biological pathways.
• Material Science: Potential intermediate for creating specialty polymers or organic electronic materials with unique properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.
• Academic & Institutional Research: Provided to university and government laboratories for fundamental research in heterocyclic and medicinal chemistry.

Basic Information

Product Name	4-Chloro-2-Diethylamino-6-(4-Methylpiperazino)-5-(Methylthio)Pyrimidine
CAS No.	63673-37-0
Molecular Formula	C14H25ClN5S
Molecular Weight	330.90 g/mol
Synonyms	4-Chloro-2-(diethylamino)-6-(4-methyl-1-piperazinyl)-5-(methylthio)pyrimidine; 2-(Diethylamino)-4-chloro-6-(4-methylpiperazin-1-yl)-5-(methylsulfanyl)pyrimidine; 4-Chloro-2-diethylamino-6-(4-methylpiperazino)-5-methylthiopyrimidine; 63673-37-0; 5-(Methylthio)-4-chloro-2-diethylamino-6-(4-methylpiperazino)pyrimidine
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-2-Diethylamino-6-(4-Methylpiperazino)-5-(Methylthio)Pyrimidine adheres to a strict quality management system. Every batch is analyzed using advanced techniques including HPLC, GC, and NMR to ensure identity, purity, and conformity to agreed specifications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to reliable supply and consistent quality makes us a trusted partner for your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is between 2°C and 8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.