Description

Z-Gly-Gly-Nva-Oh is a protected tetrapeptide derivative, specifically a Z-protected tripeptide with a norvaline C-terminus. This compound serves as a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled elongation of peptide chains for research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the fields of medicinal chemistry, biochemistry, and peptide-based drug discovery.

Application

• Peptide Synthesis Intermediate: A key raw material for the custom synthesis of longer, complex peptide sequences in pharmaceutical R&D.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop novel therapeutic peptides.
• Biochemical Tool Development: Employed in the creation of enzyme substrates, inhibitors, or probes for biochemical assays.
• API Development: Acts as a fragment in the synthesis of potential Active Pharmaceutical Ingredients (APIs) for preclinical studies.
• Academic Research: Utilized in university and institutional labs for fundamental studies in peptide science and organic chemistry.

Basic Information

Product Name	Z-Gly-Gly-Nva-Oh
CAS No.	63623-61-0
Molecular Formula	C17H23N3O6
Molecular Weight	365.38 g/mol
Synonyms	Z-Gly-Gly-Nva-OH; Nα-Carbobenzoxy-glycyl-glycyl-L-norvaline; Benzyloxycarbonyl-Gly-Gly-L-Nva-OH; Cbz-Gly-Gly-L-Nva-OH; Z-Gly-Gly-L-Norvaline; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-((tert-butoxycarbonyl)amino)pentanoic acid (Related Fmoc variant); N-[(Benzyloxy)carbonyl]glycylglycyl-L-norvaline; Glycine, N-[(benzyloxy)carbonyl]glycyl-L-norvalyl-
EINECS	Contact for details

Quality Control

Our Z-Gly-Gly-Nva-Oh is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be kept under dry, inert conditions to maintain stability and purity. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% (L-Isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.