Description

2-Chloro-4-(Thiophen-3-Yl)Pyrimidine is a high-value heterocyclic building block, a pyrimidine derivative functionalized with both a chloro and a thiophene group. This compound is essential for medicinal chemistry research and pharmaceutical development, serving as a versatile intermediate for constructing complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require a pyrimidine-thiophene core.
• Material Science: Serves as a precursor for organic electronic materials, such as organic semiconductors and light-emitting diodes (OLEDs).
• Chemical Biology: Employed as a molecular probe or a scaffold for designing enzyme inhibitors and receptor modulators.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	2-Chloro-4-(Thiophen-3-Yl)Pyrimidine
CAS No.	63558-68-9
Molecular Formula	C8H5ClN2S
Molecular Weight	196.66 g/mol
Synonyms	2-Chloro-4-(3-thienyl)pyrimidine; 4-(Thiophen-3-yl)-2-chloropyrimidine; 3-(2-Chloropyrimidin-4-yl)thiophene; Pyrimidine, 2-chloro-4-(3-thienyl)-; 2-Chloro-4-(thiophen-3-yl)pyrimidine; 2-Chloro-4-(3-thiophenyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(Thiophen-3-Yl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.