Description

5-Nitropyrimidine-4,6(1H,5H)-Dione is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its functionalized pyrimidine scaffold, which serves as a versatile precursor for the development of novel pharmacologically active compounds and agrochemicals. This intermediate is essential for R&D chemists and process development scientists working in pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality building blocks for their synthetic pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly those targeting nucleoside analogs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and plant growth regulators, leveraging its bioactive nitropyrimidine core.
• Fine Chemical Production: Serves as a versatile building block for synthesizing complex molecules in custom synthesis and contract manufacturing projects.
• Academic & Industrial Research: Employed in chemical biology and medicinal chemistry research for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the synthesis of specialized organic ligands and functional materials.

Basic Information

Product Name	5-Nitropyrimidine-4,6(1H,5H)-Dione
CAS No.	63447-42-7
Molecular Formula	C4H3N3O4
Molecular Weight	157.09 g/mol
Synonyms	5-Nitro-1H,5H-pyrimidine-4,6-dione; 5-Nitrobarbituric acid; 5-Nitro-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-Nitropyrimidine-2,4,6(1H,3H,5H)-trione; Nitrobarbituric Acid; 5-Nitro-1H-pyrimidine-4,6-dione
EINECS	Contact for details

Quality Control

Our 5-Nitropyrimidine-4,6(1H,5H)-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.