Description

Dityrosine CAS NO 63442-81-9 is a naturally occurring, cross-linked amino acid derivative formed by the oxidation of tyrosine residues. This compound serves as a critical biomarker for oxidative stress and protein damage in biological systems. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical, and nutraceutical industries for advanced biochemical studies and product development.

Application

• Biochemical Research: Used as a specific marker to study oxidative stress, protein aging, and neurodegenerative diseases like Alzheimer's and Parkinson's.
• Pharmaceutical Development: Employed in the research and quality control of therapeutic proteins and biologics to monitor stability and aggregation.
• Diagnostic Reagents: Serves as a key component or standard in ELISA kits and other assays designed to detect oxidative damage in clinical samples.
• Nutraceutical & Cosmeceutical Analysis: Used to evaluate the anti-oxidant efficacy of natural extracts, supplements, and skincare products.
• Food Science: Acts as an indicator of protein oxidation in food products, relevant for shelf-life studies and quality assurance in dairy and meat processing.
• Material Science: Investigated for the development of bio-inspired, cross-linked polymeric materials with unique mechanical properties.

Basic Information

Product Name	Dityrosine
CAS No.	63442-81-9
Molecular Formula	C18H18N2O6
Molecular Weight	358.35 g/mol
Synonyms	Bis(tyrosine); L-Dityrosine; 3,3'-Dityrosine; Di-tyrosine; Oxidized tyrosine dimer; (2S,2'S)-6,6'-Dihydroxy-5,5'-di(2-amino-2-carboxyethyl)-2,2'-biphenyl; Tyrosine dimer; H-Gly-Tyr-Tyr-OH (related peptide sequence)
EINECS	Contact for details

Quality Control

Our Dityrosine is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research-grade standards. Custom synthesis and purification to meet specific project requirements are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.