Description

(3,5-Diiodo-Tyr2,Arg8)-Vasopressin is a synthetic, iodinated analog of the neurohypophysial hormone vasopressin. This modification enhances its stability and receptor-binding profile, making it a critical research tool for studying vasopressin and oxytocin receptor systems. It is primarily utilized by pharmaceutical R&D departments, academic research institutions, and biotechnology companies focused on neuroendocrinology and peptide therapeutics.

Application

• Pharmacological Research: A key reference standard and tool compound for investigating the structure-activity relationships (SAR) of vasopressin receptor (V1a, V1b, V2) ligands.
• Biochemical Assay Development: Used in the development and validation of competitive binding assays (e.g., radioimmunoassays, RIA) and functional cellular assays for vasopressin receptors.
• Neuroscience Studies: Employed in research exploring the role of vasopressin in social behavior, stress response, memory, and autonomic regulation.
• Peptide Chemistry Reference: Serves as a model compound for studying the effects of halogenation (iodination) on peptide stability, solubility, and biological activity.
• Drug Discovery Programs: Used as a precursor or analog in the design of novel peptide-based therapeutics targeting cardiovascular, renal, or central nervous system disorders.

Basic Information

Product Name	(3,5-Diiodo-Tyr2,Arg8)-Vasopressin
CAS No.	63441-67-8
Molecular Formula	C₄₆H₆₅I₂N₁₅O₁₂S₂
Molecular Weight	1364.07 g/mol
Synonyms	[1-(Mercaptopropionic acid), 2-(3,5-diiodotyrosine), 8-arginine]vasopressin; dIYAVP; (3,5-Diiodo-Tyr(2),Arg(8))-Vasopressin; 3,5-Diiodo-Tyr2-Arg8-Vasopressin; Argipressin, 1-(3-mercaptopropanoic acid)-2-[3,5-diiodo-L-tyrosine]-8-L-arginine-; Vasopressin, [1-(3-mercaptopropanoic acid),2-(3,5-diiodo-L-tyrosine),8-L-arginine]-
EINECS	Contact for details

Quality Control

Our (3,5-Diiodo-Tyr2,Arg8)-Vasopressin is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to stringent internal quality standards to support the reliability required in pharmaceutical and academic research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular weight
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.