Description

Acetyl-D-Homophenylalanine is a high-purity, non-natural amino acid derivative characterized by its D-configuration and acetylated amine group. This chiral building block is critical for synthesizing complex peptides and pharmaceutical intermediates where stereochemical integrity is paramount. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce a hydrophobic, aromatic D-amino acid residue with a protected amine.
• Protease Inhibitor Development: Serves as a core structural component in designing and screening inhibitors for various enzymatic targets.
• Biochemical Research: Employed in studies of enzyme specificity, peptide structure-activity relationships (SAR), and chiral recognition processes.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in chromatographic analysis.

Basic Information

Product Name	Acetyl-D-Homophenylalanine
CAS No.	63393-59-9
Molecular Formula	C13H17NO3
Molecular Weight	235.28 g/mol
Synonyms	N-Acetyl-D-homophenylalanine; D-2-Acetamido-4-phenylbutanoic Acid; (R)-2-Acetamido-4-phenylbutyric Acid; N-Acetyl-D-2-amino-4-phenylbutyric Acid; Ac-D-Hph-OH; D-Homophenylalanine, N-acetyl-; N-Acetyl-D-β-homophenylalanine
EINECS	Contact for details

Quality Control

Our Acetyl-D-Homophenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.