Description

5-Bromo-4-Methylpyrimidin-2(1H)-One Hydrobromide is a high-purity pyrimidine derivative, a crucial building block in modern organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with pharmaceutical activity. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in kinase inhibitor and antiviral agent synthesis.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its halogenated pyrimidine core.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the synthesis of more complex APIs where the bromo-methylpyrimidinone moiety is integral to the final structure.
• Material Science Precursor: Potential use in the synthesis of specialized organic materials and ligands for metal-organic frameworks (MOFs).

Basic Information

Product Name	5-Bromo-4-Methylpyrimidin-2(1H)-One Hydrobromide
CAS No.	63331-36-2
Molecular Formula	C5H6BrN2O • HBr
Molecular Weight	279.93 g/mol
Synonyms	5-Bromo-4-methyl-1,2-dihydropyrimidin-2-one hydrobromide; 5-Bromo-4-methyl-2(1H)-pyrimidinone hydrobromide; 2(1H)-Pyrimidinone, 5-bromo-4-methyl-, hydrobromide; 5-Bromo-4-methylpyrimidin-2-ol hydrobromide; 4-Methyl-5-bromopyrimidin-2(1H)-one hydrobromide
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Methylpyrimidin-2(1H)-One Hydrobromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.