Description

Anti-Benzo[A]Pyrene-Guanosine-Bsa is a specialized biochemical conjugate designed for advanced research and diagnostic applications. This compound is critical for studying DNA adduct formation and the molecular mechanisms of carcinogenesis, particularly those induced by polycyclic aromatic hydrocarbons (PAHs). It serves as a vital reference standard and immunogen for researchers and quality control laboratories in the fields of toxicology, environmental monitoring, and pharmaceutical development.

Application

• Primary standard for the quantification of Benzo[a]pyrene-DNA adducts in analytical research.
• Critical reagent in the development and validation of immunoassays (ELISA) for detecting carcinogen exposure.
• Immunogen for the production of specific antibodies targeting Benzo[a]pyrene-modified guanine.
• Reference material in toxicological studies to understand PAH-induced mutagenesis and repair pathways.
• Essential component in environmental and occupational health monitoring programs.
• Used in pharmaceutical R&D for screening potential chemopreventive agents.

Basic Information

Product Name	Anti-Benzo[A]Pyrene-Guanosine-Bsa
CAS No.	63323-30-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	B[a]P-Guanosine-BSA Conjugate; Benzo[a]pyrene-guanosine-BSA; BPDE-Guanosine-Bovine Serum Albumin Conjugate; 7,8,9,10-Tetrahydrobenzo[a]pyrene-7,8-diol-9,10-epoxide-guanosine adduct conjugated to BSA; Anti-BPDE-Guo-BSA; DNA Adduct Standard (B[a]P-Guo); B[a]PDE-N2-dG-BSA
EINECS	Contact for details

Quality Control

Our Anti-Benzo[A]Pyrene-Guanosine-Bsa is produced under stringent conditions to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analysis, including verification of conjugate integrity and specificity. Certificates of Analysis (COA) detailing purity, concentration, and performance data are provided to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized solid or solution
Conjugate Identity	Confirmed (UV-Vis / HPLC)
Protein Concentration	As per COA (Bradford / BCA)
Hapten Loading (Molar Ratio)	As per COA (UV Spectroscopy)
Purity (HPLC)	≥ 95%
Solubility	Soluble in PBS, pH 7.4
Biological Activity	Reactive with specific anti-B[a]PDE antibodies (ELISA)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.