Description

[D-Met2, Pro5]-Enkephalinamide is a synthetic, biologically active peptide analog of the endogenous opioid peptide enkephalin. This compound is of significant value for research into the opioid receptor system, pain modulation, and neurological signaling pathways. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in neuropharmacology and peptide-based drug discovery.

Application

• Neuroscience Research: As a tool compound for studying the binding affinity, selectivity, and functional activity of delta (δ) and mu (μ) opioid receptors.
• Pharmacological Assays: Used in in vitro and ex vivo bioassays to investigate analgesic mechanisms and opioid peptide metabolism.
• Drug Discovery & Development: Serves as a reference standard or a lead structure in the design of novel analgesic and neuroprotective agents.
• Biochemical Studies: Employed in research on peptide stability, enzyme interactions (e.g., with peptidases), and structure-activity relationships (SAR).
• Cell Signaling Research: Useful for probing G-protein coupled receptor (GPCR) pathways and intracellular signaling cascades activated by opioid receptors.

Basic Information

Product Name	[D-Met2, Pro5]-Enkephalinamide
CAS No.	63307-63-1
Molecular Formula	C30H41N7O7S
Molecular Weight	643.8 g/mol
Synonyms	D-Met2-Pro5-Enkephalinamide; [D-Met2, Pro5]-Enkephalin; Tyr-D-Met-Gly-Phe-Pro-NH2; H-Tyr-D-Met-Gly-Phe-Pro-NH2; Opioid peptide analog; Delta opioid receptor ligand; (5S)-5-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-1-(pyrrolidine-1-carbonyl)pentyl]carbamic acid
EINECS	Contact for details

Quality Control

Our [D-Met2, Pro5]-Enkephalinamide is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to stringent internal quality standards to meet the demands of pharmaceutical and life science research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Purity (Titration)	≥ 97.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.