Description

Pyridoxal Phosphate γ-Aminobutyric Acid is a specialized biochemical compound that combines the active form of vitamin B6 with the major inhibitory neurotransmitter GABA. This product is essential for research and development in neurochemistry and metabolic studies, where it serves as a critical cofactor and precursor. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of high-purity biochemical reagents.

Application

• Neuropharmacological Research: Used as a precursor or standard in studies investigating GABAergic neurotransmission, synaptic function, and neurological disorders.
• Enzymology & Metabolic Studies: Serves as a cofactor for enzymes such as glutamate decarboxylase (GAD), crucial for studying GABA synthesis and related metabolic pathways.
• Pharmaceutical Intermediate: Employed in the research and development of potential neuroactive drugs, prodrugs, or diagnostic agents targeting the central nervous system.
• Biochemical Reagent: A key component in high-purity reagent kits and assays for clinical research, cell culture studies, and in vitro diagnostic development.
• Nutritional Science Research: Investigated for its role in the metabolic interplay between vitamin B6 activity and neurotransmitter regulation.

Basic Information

Product Name	Pyridoxal Phosphate γ-Aminobutyric Acid
CAS No.	63221-68-1
Molecular Formula	C11H17N2O8P
Molecular Weight	336.24 g/mol
Synonyms	PLP-GABA; Pyridoxal 5'-Phosphate GABA; GABA-Pyridoxal Phosphate Conjugate; 4-[[(4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methoxy]hydroxyphosphoryl]oxy-4-aminobutanoic Acid; Vitamin B6 Phosphate GABA Derivative; Pyridoxal-P-GABA; γ-Aminobutyric Acid Pyridoxal Phosphate Ester
EINECS	Contact for details

Quality Control

Our Pyridoxal Phosphate γ-Aminobutyric Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.