Description

L-Norleucine, Phenylmethyl Ester is a protected amino acid derivative, specifically the benzyl ester of L-norleucine. This compound is a crucial chiral building block in organic synthesis, valued for its role in constructing complex peptide structures and other bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for applications in drug discovery and process development.

Application

• Pharmaceutical Intermediates: Key starting material or intermediate in the synthesis of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected amino acid building block to incorporate the norleucine residue.
• Biochemical Research: Employed in proteomics and metabolic studies as a non-natural amino acid analog to investigate protein structure, function, and stability.
• Fine Chemical Production: Serves as a chiral synthon for the preparation of complex organic molecules, including catalysts and ligands for asymmetric synthesis.
• Reference Standards: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	L-Norleucine, Phenylmethyl Ester
CAS No.	63219-54-5
Molecular Formula	C13H19NO2
Molecular Weight	221.30 g/mol
Synonyms	L-Norleucine benzyl ester; (S)-2-Aminohexanoic acid benzyl ester; Benzyl L-norleucinate; H-Nle-OBzl; Norleucine, L-, benzyl ester; L-2-Aminohexanoic acid phenylmethyl ester; L-α-Aminocaproic acid benzyl ester; L-Norleucine benzyl ester tosylate salt (common derivative)
EINECS	Contact for details

Quality Control

Our L-Norleucine, Phenylmethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Melting Point	Contact for details
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.