Description

2,4-Dichloro-5H-Pyrrolo[3,2-D]Pyrimidine is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its versatile reactivity, where the chlorine atoms serve as excellent leaving groups for nucleophilic aromatic substitution, enabling the construction of complex molecular architectures. This compound is critically needed by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, particularly in kinase inhibitor and antiviral research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient pyrrolopyrimidine structure.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological processes and target validation.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring functionalized pyrrolopyrimidine scaffolds.

Basic Information

Product Name	2,4-Dichloro-5H-Pyrrolo[3,2-D]Pyrimidine
CAS No.	63200-54-4
Molecular Formula	C6H3Cl2N3
Molecular Weight	188.01 g/mol
Synonyms	2,4-Dichloro-5H-pyrrolo[3,2-d]pyrimidine; 5H-Pyrrolo[3,2-d]pyrimidine, 2,4-dichloro-; 2,4-Dichloropyrrolo[3,2-d]pyrimidine; Pyrrolo[3,2-d]pyrimidine, 2,4-dichloro-; 63200-54-4; 2,4-Dichloro-7-azaindole; 2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine (common mislabeling); 2,4-Dichloro-1H-pyrrolo[3,2-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-5H-Pyrrolo[3,2-D]Pyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and MS confirmation, to support your regulatory and R&D requirements. Certificates of Analysis (COA) are available for every batch upon request, detailing all relevant specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.