Description

8-Chloro-6-(2-Chlorophenyl)-4H-Imidazo(1,5-A)(1,4)-Benzodiazepine-3-Carboxamide is a high-purity benzodiazepine derivative, a critical intermediate in advanced pharmaceutical synthesis. Its value lies in its precise molecular structure, which is essential for research and development of novel therapeutic agents. This compound is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing central nervous system (CNS) active compounds and other specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new therapeutic candidates.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical manufacturing.
• Preclinical Studies: Employed in pharmacological and toxicological research to investigate the properties of new chemical entities.
• Process Chemistry: Utilized for scaling up synthetic routes and optimizing production processes for target molecules.
• Academic Research: A valuable compound for university and institutional research into heterocyclic chemistry and neuropharmacology.

Basic Information

Product Name	8-Chloro-6-(2-Chlorophenyl)-4H-Imidazo(1,5-A)(1,4)-Benzodiazepine-3-Carboxamide
CAS No.	63176-94-3
Molecular Formula	C₁₈H₁₂Cl₂N₄O
Molecular Weight	371.22 g/mol
Synonyms	8-Chloro-6-(2-chlorophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxamide; 63176-94-3; Imidazobenzodiazepine carboxamide derivative; Ro 15-4513 (related precursor); 8-Chloro-6-(o-chlorophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxamide; 4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxamide, 8-chloro-6-(2-chlorophenyl)-; Benzodiazepine imidazole carboxamide
EINECS	Contact for details

Quality Control

Our 8-Chloro-6-(2-Chlorophenyl)-4H-Imidazo(1,5-A)(1,4)-Benzodiazepine-3-Carboxamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.