Description

H-Val-Gly-Asp-Glu-Oh CAS NO 63141-66-2 is a high-purity tetrapeptide sequence containing valine, glycine, aspartic acid, and glutamic acid. This compound is a critical building block in pharmaceutical research and development, particularly for designing novel bioactive molecules and enzyme substrates. It is essential for researchers and manufacturers in the fields of peptide synthesis, medicinal chemistry, and biochemical studies who require reliable, high-quality raw materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor for the development of new therapeutic peptides and peptidomimetics.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate protease and peptidase activity.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize peptide-based drug candidates.
• Peptide Library Synthesis: A valuable component in combinatorial chemistry for creating diverse peptide libraries for screening.
• Cell Adhesion Studies: The Asp-Glu sequence may be investigated for its role in mimicking cell adhesion motifs.
• Reference Standard: Used as an analytical standard in quality control laboratories for peptide identification and quantification.

Basic Information

Product Name	H-Val-Gly-Asp-Glu-Oh
CAS No.	63141-66-2
Molecular Formula	C17H27N5O9
Molecular Weight	445.43 g/mol
Synonyms	Val-Gly-Asp-Glu; VGDE Tetrapeptide; L-Valyl-glycyl-L-α-aspartyl-L-glutamic acid; H-Val-Gly-Asp-Glu-OH; Tetrapeptide VGDE; Aspartylglutamylglycylvaline; (S)-2-((S)-2-((2-((S)-2-Amino-3-methylbutanamido)acetamido)-3-carboxypropanamido)pentanedioic acid
EINECS	Contact for details

Quality Control

Our H-Val-Gly-Asp-Glu-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for residual solvents and heavy metals, to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.