Description

Tuftsin, Lys(4)- CAS NO 63138-91-0 is a synthetic tetrapeptide derivative of the natural immunomodulatory peptide Tuftsin, specifically modified with an additional lysine residue at the fourth position. This modification is designed to enhance its stability and biological activity, making it a valuable tool for immunological research and therapeutic development. It is primarily utilized by researchers and developers in the pharmaceutical and biotechnology sectors for studying macrophage activation, immunostimulation, and potential applications in vaccine adjuvants and cancer immunotherapy.

Application

• Immunological Research: Fundamental studies on macrophage function, phagocytosis, and cytokine release.
• Drug Discovery: Screening and development of novel immunomodulatory agents and anti-infective therapies.
• Vaccine Adjuvant Development: Investigation as a potential component to enhance the efficacy of vaccine formulations.
• Cancer Immunotherapy: Research into stimulating the immune system to target and eliminate cancer cells.
• Biochemical Reagent: Use as a high-purity standard or reference compound in analytical laboratories.
• Peptide Chemistry Studies: Serving as a model compound for studying structure-activity relationships (SAR) in peptide design.

Basic Information

Product Name	Tuftsin, Lys(4)- CAS NO 63138-91-0
CAS No.	63138-91-0
Molecular Formula	C26H48N10O7
Molecular Weight	612.73 g/mol
Synonyms	Lys4-Tuftsin; [Lys4]-Tuftsin; Thr-Lys-Pro-Lys; TKPK; H-Thr-Lys-Pro-Lys-OH; Tuftsin (Lys4); L-Threonyl-L-lysyl-L-prolyl-L-lysine; Immunostimulant peptide TKPK
EINECS	Contact for details

Quality Control

Our Tuftsin, Lys(4)- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for peptide synthesis and can provide material for research use under quality commitments aligned with GMP principles where required.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.