Description

L-Proline, 3,4-Dihydroxy- (9Ci) is a hydroxylated derivative of the amino acid proline, offering unique structural and functional properties for advanced chemical synthesis and research. This compound is valued for its role as a specialized chiral building block and intermediate in the development of complex molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for applications requiring high-purity, stereochemically defined intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in protease inhibitor and cardiovascular drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and for probing biological pathways related to collagen synthesis and hydroxylase activity.
• Peptide Synthesis: Serves as a modified amino acid residue in solid-phase and solution-phase peptide synthesis to introduce conformational constraints or functional groups into peptide chains.
• Agrochemical Development: Employed as a building block in the synthesis of advanced, bioactive compounds for crop protection and plant growth regulation.
• Fine Chemical Synthesis: Acts as a versatile intermediate for creating complex natural product analogs, catalysts, and specialty chemicals.

Basic Information

Product Name	L-Proline, 3,4-Dihydroxy- (9Ci)
CAS No.	63121-50-6
Molecular Formula	C5H9NO4
Molecular Weight	147.13 g/mol
Synonyms	3,4-Dihydroxy-L-proline; (2S,3S,4S)-3,4-Dihydroxypyrrolidine-2-carboxylic acid; L-3,4-Dihydroxyproline; 3-Hydroxy-4-hydroxy-L-proline; cis-3,4-Dihydroxy-L-proline; L-cis-3,4-Dihydroxyproline; (2S,3S,4S)-3,4-Dihydroxyproline
EINECS	Contact for details

Quality Control

Our L-Proline, 3,4-Dihydroxy- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), chiral purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.