Description

(+/-)-Threo-3-Methylglutamic Acid is a non-proteinogenic glutamic acid derivative characterized by its unique stereochemistry and methyl substitution. This compound serves as a valuable chiral building block and biochemical tool in advanced research and synthesis. It is primarily utilized by pharmaceutical researchers, agrochemical developers, and academic institutions working on neuroscience, metabolic pathway studies, and the development of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel drugs, particularly those targeting neurological receptors and metabolic enzymes.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate glutamate metabolism and related pathways.
• Neuroscience Probes: Employed in the study of glutamate transporters (EAATs) and ionotropic glutamate receptors due to its structural similarity to glutamate.
• Agrochemical Development: Serves as a precursor for synthesizing advanced, biologically active compounds with potential herbicidal or plant growth regulatory properties.
• Peptide Modification: Incorporated into synthetic peptides to alter their conformation, stability, and biological activity for therapeutic or diagnostic applications.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	(+/-)-Threo-3-Methylglutamic Acid
CAS No.	63088-04-0
Molecular Formula	C6H11NO4
Molecular Weight	161.16 g/mol
Synonyms	DL-threo-3-Methylglutamic Acid; (±)-threo-3-Methylglutamic Acid; 3-Methyl-DL-glutamic Acid; 2-Amino-3-methylpentanedioic Acid; 3-Methylglutamic Acid (racemic threo isomer); NSC 113928; (2R*,3S*)-2-Amino-3-methylpentanedioic acid; (2S*,3R*)-2-Amino-3-methylpentanedioic acid
EINECS	Contact for details

Quality Control

Our (+/-)-Threo-3-Methylglutamic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure identity, potency, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99:1 threo:erythro ratio
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.