Description

Poly-D-Leucine is a synthetic, non-natural enantiomer of the essential amino acid leucine, specifically engineered for applications requiring the D-configuration. This compound matters for its role in advanced research and development, particularly in the study of chiral recognition, peptide stability, and as a building block for specialized bioactive peptides. It is needed by pharmaceutical R&D teams, academic researchers in biochemistry, and manufacturers of high-purity chiral reagents and standards.

Application

• As a chiral building block in the research and synthesis of non-natural peptides and peptidomimetics.
• For use in biochemical studies investigating enzyme specificity, protein folding, and chiral recognition mechanisms.
• As a standard or reference material in analytical chemistry for chiral separation techniques like HPLC.
• In the development of specialized materials where the D-amino acid configuration imparts different physical or biological properties.
• For pharmaceutical research exploring the metabolic stability and biological activity of D-amino acid-containing compounds.

Basic Information

Product Name	Poly-D-Leucine
CAS No.	63038-44-8
Molecular Formula	(C6H13NO2)n
Molecular Weight	Variable (Polymer)
Synonyms	D-Leucine Homopolymer; Poly(D-leucine); PDL; (R)-2-Amino-4-methylpentanoic acid homopolymer; D-Poly(leucine); Poly-D-leucine; Poly(D-leucine) (homopolymer); D-Leucine polymer
EINECS	Contact for details

Quality Control

Our Poly-D-Leucine is produced under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing. Certificates of Analysis (COA) detailing purity, molecular weight distribution, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 95% (D-isomer content)
Specific Rotation	Contact for details
Moisture Content	≤ 5.0%
Molecular Weight Range	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.