Description

6-(1-Aziridinyl)-4-Chloro-2-Phenylpyrimidine is a specialized heterocyclic building block featuring both a pyrimidine core and a reactive aziridine moiety. This unique structure makes it a valuable intermediate for the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for constructing novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially those targeting kinases or other enzymes.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides due to its bioactive pyrimidine structure.
• Chemical Biology Probes: Serves as a precursor for creating molecular probes to study biological pathways and protein functions.
• Material Science: Potential monomer or cross-linking agent in the development of advanced polymers with specific functionalities.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploratory synthetic chemistry.

Basic Information

Product Name	6-(1-Aziridinyl)-4-Chloro-2-Phenylpyrimidine
CAS No.	63019-51-2
Molecular Formula	C12H10ClN3
Molecular Weight	231.68 g/mol
Synonyms	4-Chloro-6-(aziridin-1-yl)-2-phenylpyrimidine; 2-Phenyl-4-chloro-6-(1-aziridinyl)pyrimidine; 4-Chloro-2-phenyl-6-(aziridin-1-yl)pyrimidine; 6-Aziridin-1-yl-4-chloro-2-phenyl-pyrimidine; Aziridine, 1-(4-chloro-2-phenyl-6-pyrimidinyl)-; 63019-51-2; 4-Chloro-6-aziridin-1-yl-2-phenylpyrimidine
EINECS	Contact for details

Quality Control

Every batch of 6-(1-Aziridinyl)-4-Chloro-2-Phenylpyrimidine is produced and tested under strict quality management protocols. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical R&D and scale-up processes. A Certificate of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and physical characteristics is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.