Description

Dnp-Pro-Gln-Gly-Ile-Ala-Gly-Gln-D-Arg-Oh is a synthetic, chemically modified peptide sequence of significant interest in advanced biochemical research and development. This compound, identified by CAS number 63014-08-4, serves as a critical building block and a specialized tool for studying peptide structure, function, and interactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in proteomics, enzyme-substrate studies, and the development of novel therapeutic agents. Its unique sequence, featuring a D-arginine residue and a dinitrophenyl (Dnp) protecting group, makes it valuable for targeted investigations in signal transduction and molecular recognition pathways.

Application

• Biochemical Research: Used as a standard, substrate, or inhibitor in enzymatic assays and kinetic studies to understand specific protease activities.
• Pharmaceutical R&D: Serves as a key intermediate or a model compound in the design and screening of new peptide-based drugs and diagnostic agents.
• Proteomics & Structural Biology: Employed in studies of protein-protein interactions, peptide folding, and the analysis of binding affinities using techniques like surface plasmon resonance (SPR).
• Antibody Production: Can be used as a hapten to generate specific antibodies for immunoassay development and immunological research.
• Academic Research: A vital tool in university laboratories for graduate and post-graduate studies focused on peptide chemistry and molecular biology.
• Method Development: Acts as a reference material for developing and validating new analytical methods in chromatography (HPLC, LC-MS) and spectroscopy.

Basic Information

Product Name	Dnp-Pro-Gln-Gly-Ile-Ala-Gly-Gln-D-Arg-Oh
CAS No.	63014-08-4
Molecular Formula	C46H68N16O16
Molecular Weight	1061.1 g/mol
Synonyms	N-2,4-Dinitrophenyl-L-prolyl-L-glutaminylglycyl-L-isoleucyl-L-alanylglycyl-L-glutaminyl-D-arginine; DNP-Pro-Gln-Gly-Ile-Ala-Gly-Gln-D-Arg-OH; Dnp-Pro-Gln-Gly-Ile-Ala-Gly-Gln-D-Arg; 2,4-DNP-Pro-Gln-Gly-Ile-Ala-Gly-Gln-D-Arg; Peptide Dnp-PQGIGQ-D-Arg; Modified Peptide Substrate; Dnp-Protected Peptide; D-Arg containing peptide
EINECS	Contact for details

Quality Control

Every batch of Dnp-Pro-Gln-Gly-Ile-Ala-Gly-Gln-D-Arg-Oh is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocol includes advanced chromatographic and spectroscopic methods. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications such as purity (by HPLC), amino acid analysis, and mass spectrometry confirmation. We adhere to stringent in-house standards suitable for research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular weight
Purity (HPLC)	≥ 95.0%
Amino Acid Analysis	Passes test
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.