Description

Ethyl 1,4-Dihydro-8-Fluoro-4-Oxoquinoline-3-Carboxylate is a high-purity fluorinated quinolone derivative, serving as a critical advanced pharmaceutical intermediate. Its core value lies in enabling the synthesis of next-generation antibacterial agents, offering a reliable building block for complex molecular architectures. This compound is essential for research institutions and manufacturers in the pharmaceutical and fine chemical sectors developing novel fluoroquinolone antibiotics.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potent fluoroquinolone antibiotic APIs (Active Pharmaceutical Ingredients).
• Antibacterial Research: Used in R&D for developing new antibacterial compounds with improved efficacy and spectrum of activity.
• Fine Chemical Synthesis: Building block for creating complex heterocyclic compounds in medicinal chemistry.
• Process Development: Serves as a standard or starting material for scaling up and optimizing antibiotic manufacturing processes.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for studying structure-activity relationships (SAR) of quinolone derivatives.

Basic Information

Product Name	Ethyl 1,4-Dihydro-8-Fluoro-4-Oxoquinoline-3-Carboxylate
CAS No.	63010-69-5
Molecular Formula	C₁₂H₁₀FNO₃
Molecular Weight	235.21 g/mol
Synonyms	8-Fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; Ethyl 8-Fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate; 8-Fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid Ethyl Ester; 1,4-Dihydro-8-fluoro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; Ethyl 8-Fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate; 63010-69-5; Quinolone Derivative Intermediate
EINECS	Contact for details

Quality Control

Our Ethyl 1,4-Dihydro-8-Fluoro-4-Oxoquinoline-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.