Description

3-Amino-2-(4-chlorophenyl)-3,4-dihydroquinazolin-4-one is a specialized quinazolinone derivative, a high-value chemical intermediate prized for its heterocyclic structure. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or insecticides, leveraging its quinazolinone core for biological activity.
• Fine Chemical Synthesis: Serves as a versatile scaffold for constructing complex heterocyclic compounds in custom synthesis and contract manufacturing.
• Academic & Institutional R&D: Employed in medicinal chemistry programs and biochemical studies to explore structure-activity relationships (SAR).
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions.

Basic Information

Product Name	3-Amino-2-(4-Chlorophenyl)-3,4-Dihydroquinazolin-4-One
CAS No.	63002-70-0
Molecular Formula	C14H10ClN3O
Molecular Weight	271.70 g/mol
Synonyms	3-Amino-2-(4-chlorophenyl)-3,4-dihydro-4-quinazolinone; 2-(4-Chlorophenyl)-3-amino-3,4-dihydroquinazolin-4-one; 4(3H)-Quinazolinone, 3-amino-2-(4-chlorophenyl)-3,4-dihydro-; 3-Amino-2-(p-chlorophenyl)-3,4-dihydro-4-quinazolinone; ACDQ; Quinazolinone derivative 63002-70-0
EINECS	Contact for details

Quality Control

Our 3-Amino-2-(4-chlorophenyl)-3,4-dihydroquinazolin-4-one is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storage under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.