Description

5-Bromo-4-Chloro-2-Piperidin-1-Ylpyrimidine is a high-purity, heterocyclic organic compound featuring a pyrimidine core substituted with bromo, chloro, and piperidinyl groups, serving as a critical building block in advanced chemical synthesis. Its precise molecular architecture makes it an invaluable intermediate for the development of novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular frameworks.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides that require specific halogenated heterocyclic structures.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials, ligands for catalysis, and other functionalized polymers.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.

Basic Information

Product Name	5-Bromo-4-Chloro-2-Piperidin-1-Ylpyrimidine
CAS No.	62880-68-6
Molecular Formula	C9H10BrClN3
Molecular Weight	275.55 g/mol
Synonyms	5-Bromo-4-chloro-2-(1-piperidinyl)pyrimidine; 2-Piperidino-5-bromo-4-chloropyrimidine; 4-Chloro-5-bromo-2-piperidin-1-ylpyrimidine; 5-Bromo-4-chloro-2-piperidinopyrimidine; 62880-68-6; 5-Bromo-4-chloro-2-(piperidin-1-yl)pyrimidine
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-4-Chloro-2-Piperidin-1-Ylpyrimidine is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications, which are aligned with industry best practices for advanced intermediates. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.