Description

(S)-n-(1-(2,3-Dihydroxypropyl)-2-Oxo-1,2-Dihydropyrimidin-4-Yl)Benzamide CAS NO 62853-19-4 is a high-purity chiral pyrimidine derivative, a sophisticated organic building block critical for advanced pharmaceutical research and development. Its value lies in its role as a key intermediate for synthesizing novel therapeutic agents, particularly in antiviral and anticancer drug discovery programs. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require highly specific, enantiomerically pure intermediates to develop next-generation treatments.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of novel nucleoside/nucleotide analogs for antiviral and anticancer therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery projects targeting viral polymerases or specific cellular enzymes.
• Process Chemistry Development: Employed in scaling up synthetic routes for Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Biochemical Research: Acts as a substrate or inhibitor in enzymatic assays to study biological pathways and mechanisms of action.
• Fine Chemical Synthesis: Utilized as a specialty intermediate for creating complex, high-value molecules in custom synthesis and contract manufacturing.

Basic Information

Product Name	(S)-n-(1-(2,3-Dihydroxypropyl)-2-Oxo-1,2-Dihydropyrimidin-4-Yl)Benzamide
CAS No.	62853-19-4
Molecular Formula	C14H15N3O4
Molecular Weight	289.29 g/mol
Synonyms	(S)-N-[1-(2,3-Dihydroxypropyl)-2-oxo-1,2-dihydropyrimidin-4-yl]benzamide; 4-Benzamidouracil Derivative; (S)-4-(Benzoylamino)-1-(2,3-dihydroxypropyl)pyrimidin-2(1H)-one; (S)-1-(2,3-Dihydroxypropyl)-4-(benzoylamino)-2(1H)-pyrimidinone; Benzamide, N-[1-(2,3-dihydroxypropyl)-2-oxo-1,2-dihydro-4-pyrimidinyl]-, (S)-; (S)-enantiomer of the pyrimidine benzamide derivative
EINECS	Contact for details

Quality Control

Our production of (S)-n-(1-(2,3-Dihydroxypropyl)-2-Oxo-1,2-Dihydropyrimidin-4-Yl)Benzamide adheres to stringent quality management systems, ensuring batch-to-batch consistency for critical R&D and scale-up applications. The material is characterized and released using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support compliance with relevant regulatory frameworks for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.