Description

2,4(1H,3H)-Pyrimidinedione, 6-[[3-[4-(2-Methoxyphenyl)-1-Oxido-1-Piperazinyl]Propyl]Amino]-1,3-Dimethyl- is a high-purity, synthetically derived pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of advanced active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules, particularly those targeting the central nervous system.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new pharmacologically active compounds.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core scaffold or a functionalized intermediate in the production of proprietary APIs under current investigation.
• Biochemical Research: Potential use as a tool compound in biochemical assays to study specific enzyme interactions or receptor binding.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	2,4(1H,3H)-Pyrimidinedione, 6-[[3-[4-(2-Methoxyphenyl)-1-Oxido-1-Piperazinyl]Propyl]Amino]-1,3-Dimethyl-
CAS No.	62845-30-1
Molecular Formula	C20H29N5O4
Molecular Weight	403.48 g/mol
Synonyms	6-[[3-[4-(2-Methoxyphenyl)-1-oxido-1-piperazinyl]propyl]amino]-1,3-dimethylpyrimidine-2,4(1H,3H)-dione; 1,3-Dimethyl-6-({3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl}amino)pyrimidine-2,4(1H,3H)-dione 1-oxide; 6-({3-[4-(2-Methoxyphenyl)piperazin-1-yl]propyl}amino)-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 1-oxide; A derivative of 1,3-dimethyl-6-aminouracil.
EINECS	Contact for details

Quality Control

Our production of this pharmaceutical intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot. We support development projects with material produced under GMP-like conditions upon request, ensuring suitability for advanced research and pre-clinical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; therefore, the container should be kept tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.