Description

2-Chloro-N,n-Dimethylpyrimidin-5-Amine is a versatile pyrimidine derivative, a key heterocyclic building block prized for its reactive chloro and dimethylamino substituents. This compound matters for its crucial role in facilitating the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various drug candidates, particularly those targeting kinase inhibition and other therapeutic areas.
• Agrochemical Synthesis: Used as a key building block for creating novel herbicides, fungicides, and insecticides with specific modes of action.
• Organic Synthesis Reagent: Serves as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution reactions.
• Material Science Research: Employed in the development of organic semiconductors, ligands for catalysts, and other functional organic materials.
• Chemical Biology Probe Development: Utilized to create molecular probes for studying biological pathways and protein functions.

Basic Information

Product Name	2-Chloro-N,n-Dimethylpyrimidin-5-Amine
CAS No.	62802-43-1
Molecular Formula	C6H9ClN4
Molecular Weight	172.61 g/mol
Synonyms	5-Amino-2-chloro-N,N-dimethylpyrimidine; 2-Chloro-5-(dimethylamino)pyrimidine; 2-Chloro-5-(N,N-dimethylamino)pyrimidine; N,N-Dimethyl-2-chloropyrimidin-5-amine; 2-Chloro-N,N-dimethyl-5-pyrimidinamine; 5-(Dimethylamino)-2-chloropyrimidine; 2-Chloro-5-(dimethylamino)-pyrimidine; 2-Chloro-5-dimethylaminopyrimidine
EINECS	Contact for details

Quality Control

Our 2-Chloro-N,n-Dimethylpyrimidin-5-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.