Description

2-Fluoro-5-Nitropyrimidine is a high-purity, heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its dual functionalization, featuring both a fluorine substituent and a nitro group, which makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated pyrimidine-based drug candidates, including potential kinase inhibitors and antiviral agents.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging the biological activity of the fluoronitropyrimidine scaffold.
• Material Science: Serves as a building block for creating specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: Employed in cross-coupling reactions and nucleophilic aromatic substitution (SNAr) to introduce the pyrimidine core into more complex molecules.
• Academic & R&D: A valuable reagent for methodological studies in fluorine chemistry and heterocyclic compound synthesis.

Basic Information

Product Name	2-Fluoro-5-Nitropyrimidine
CAS No.	62802-41-9
Molecular Formula	C4H2FN3O2
Molecular Weight	143.08 g/mol
Synonyms	5-Nitro-2-fluoropyrimidine; 2-Fluoro-5-nitropyrimidine; 2-Fluoropyrimidine-5-nitro; Pyrimidine, 2-fluoro-5-nitro-; 5-Nitro-2-fluoro-pyrimidine; 62802-41-9 (CAS); Fluoronitropyrimidine
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Nitropyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee consistent quality and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.