Description

5-Bromo-2-Fluoropyrimidine is a versatile and high-value halogenated pyrimidine building block essential for modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nucleoside analogs, kinase inhibitors, and other small-molecule drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a building block for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, tags, and activity-based probes (ABPs) for studying biological systems.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Nucleic Acid Chemistry: Useful in the modification of oligonucleotides for therapeutic and diagnostic applications.

Basic Information

Product Name	5-Bromo-2-Fluoropyrimidine
CAS No.	62802-38-4
Molecular Formula	C4H2BrFN2
Molecular Weight	176.97 g/mol
Synonyms	2-Fluoro-5-bromopyrimidine; 5-Bromo-2-fluoropyrimidine; 2-Fluoro-5-bromo-1,3-diazine; Pyrimidine, 5-bromo-2-fluoro-; 5-Brom-2-fluorpyrimidin (German); 5-ブロモ-2-フルオロピリミジン (Japanese)
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluoropyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.