Description

Pyrimidine, 5-Chloro-2-Fluoro- (9Ci) is a halogenated pyrimidine derivative, a crucial heterocyclic building block in advanced organic synthesis. Its precise molecular architecture makes it an indispensable intermediate for creating complex molecules with targeted biological and material properties. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel antiviral, anticancer, and antimicrobial agents, leveraging the pyrimidine core's bioactivity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Biology & Proteomics: Employed as a building block for synthesizing molecular probes, tags, and inhibitors for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring functionalized pyrimidine scaffolds.
• Academic & Industrial R&D: Utilized in discovery chemistry for exploring new chemical spaces and reaction methodologies.

Basic Information

Item	Detail
Product Name	Pyrimidine, 5-Chloro-2-Fluoro- (9Ci)
CAS No.	62802-37-3
Molecular Formula	C4H2ClFN2
Molecular Weight	132.52 g/mol
Synonyms	5-Chloro-2-fluoropyrimidine; 2-Fluoro-5-chloropyrimidine; 5-Chloro-2-fluoro-1,3-diazine; 2-Fluoro-5-chloro-1,3-diazine; 5-Chloro-2-fluoropyrimidine (9CI); 5-Chloro-2-fluoro-pyrimidine; 2-Fluoro-5-chloro-1,3-diazabenzene
EINECS	Contact for details

Quality Control

Our Pyrimidine, 5-Chloro-2-Fluoro- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to quality supports applications requiring high-purity intermediates for GMP or research-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is sensitive to fluoride and strong alkali; ensure storage areas are free from such incompatible materials. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.