Description

n-Acetylamrinone CAS NO 62749-47-7 is a high-purity synthetic organic compound, specifically an acetylated derivative of amrinone. This chemical serves as a critical intermediate in advanced pharmaceutical synthesis, enabling the development of specialized cardiovascular and inotropic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic compounds and fine chemical production.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of specialized cardiovascular drugs and inotropic agents.
• Biochemical Research: Used as a reference standard or precursor in pharmacological and metabolic pathway studies.
• Fine Chemical Synthesis: Serves as a versatile intermediate for creating complex molecules in medicinal chemistry.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for investigating structure-activity relationships (SAR).

Basic Information

Product Name	n-Acetylamrinone
CAS No.	62749-47-7
Molecular Formula	C12H9N3O3
Molecular Weight	243.22 g/mol
Synonyms	1,6-Dihydro-2-methyl-6-oxo-[3,4'-bipyridine]-5-carbonitrile, 3-Acetyl-1,2-dihydro-5-(4-pyridinyl)-2-oxo-3H-indole-3-carbonitrile, Amrinone Impurity C, Acetyl Amrinone, 3-Acetylamrinone, 5-Cyano-1,6-dihydro-2-methyl-6-oxo-3-(4-pyridyl)pyridine, 3-Acetyl-5-cyano-1,6-dihydro-2-methyl-6-oxo-3-(4-pyridinyl)pyridine
EINECS	Contact for details

Quality Control

Our n-Acetylamrinone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.