Description

H-Trp-Pro-Pro-Tyr-Oh is a synthetic tetrapeptide sequence composed of Tryptophan, Proline, Proline, and Tyrosine residues. This compound is of significant interest in biochemical research and pharmaceutical development due to its specific amino acid motif, which can influence protein-protein interactions and biological activity. It serves as a critical intermediate or reference standard for researchers in peptide synthesis, drug discovery, and proteomics.

Application

• Pharmaceutical Research & Development: Used as a building block or reference standard in the synthesis of novel therapeutic peptides and peptidomimetics.
• Biochemical Assay Development: Serves as a substrate or inhibitor in enzymatic studies to investigate protease specificity and kinetics.
• Proteomics & Structural Biology: Employed in studies of protein folding, stability, and molecular recognition due to its Proline-rich sequence.
• Cosmeceutical Ingredient Research: Investigated for potential bioactive properties in skin care formulations, such as anti-aging or signaling modulation.
• Academic & Institutional Research: A key reagent for universities and research institutes studying peptide chemistry and cell signaling pathways.
• Quality Control & Analytical Standards: Used as a high-purity certified reference material (CRM) for calibrating analytical instruments like HPLC and Mass Spectrometry.

Basic Information

Product Name	H-Trp-Pro-Pro-Tyr-Oh
CAS No.	62690-33-9
Molecular Formula	C33H40N6O6
Molecular Weight	616.71 g/mol
Synonyms	H-Trp-Pro-Pro-Tyr-OH; Tryptophyl-Prolyl-Prolyl-Tyrosine; WPPY; Tetrapeptide Trp-Pro-Pro-Tyr; L-Tryptophyl-L-prolyl-L-prolyl-L-tyrosine; TPPY; H-Tryptophan-Proline-Proline-Tyrosine-OH; (S)-2-((S)-1-((S)-1-((S)-1-Carboxy-2-(1H-indol-3-yl)ethyl)amino)-1-oxopropan-2-yl)pyrrolidine-2-carboxamido)-3-(4-hydroxyphenyl)propanoic acid
EINECS	Contact for details

Quality Control

Our H-Trp-Pro-Pro-Tyr-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.