Description

H-Arg-Ile-Oh Acetate Salt is a high-purity, protected dipeptide derivative, specifically the acetate salt form of the H-Arg-Ile-OH peptide. This compound is a critical building block in solid-phase peptide synthesis (SPPS), offering enhanced solubility and handling characteristics for the controlled assembly of complex peptide sequences. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediate: Key raw material for the synthesis of longer, biologically active peptide chains for drug discovery and development.
• Biochemical Research: Used as a standard or reagent in proteomics research, enzyme-substrate studies, and structure-activity relationship (SAR) investigations.
• Peptide Library Synthesis: A fundamental component in the combinatorial chemistry production of diverse peptide libraries for high-throughput screening.
• Cosmetic Peptide Synthesis: Employed in the manufacture of specialized peptide ingredients for advanced skincare and cosmetic formulations.
• Academic Research: Serves as a teaching and research tool in university laboratories for studies in organic chemistry, peptide chemistry, and medicinal chemistry.

Basic Information

Product Name	H-Arg-Ile-Oh Acetate Salt
CAS No.	62632-70-6
Molecular Formula	C15H30N6O4 • xC2H4O2
Molecular Weight	374.44 g/mol (free base) + Acetate
Synonyms	H-Arg-Ile-OH • AcOH; L-Arginyl-L-isoleucine acetate salt; Nα-Boc-Nω-Pbf-L-arginyl-L-isoleucine acetate; Boc-Arg(Pbf)-Ile-OH acetate; (S)-2-((S)-5-((2,2,4,6,7-Pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)-2-((tert-butoxycarbonyl)amino)pentanoyl)amino)-3-methylpentanoic acid acetate; Protected Arginine-Isoleucine Dipeptide Acetate; Boc-Arg(Pbf)-Ile-OHAc; Peptide Synthesis Building Block R-I
EINECS	Contact for details

Quality Control

Our H-Arg-Ile-Oh Acetate Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and NMR for structural confirmation, to ensure it meets the stringent requirements for peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your research or cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This product is hygroscopic (moisture-sensitive); desiccants are recommended for long-term storage. Keep container tightly sealed under an inert atmosphere when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Acetate Content (Titration)	1.0 - 2.0 eq
Heavy Metals (ICP-MS)	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.