Description

2',4'-Difluoro-Biphenyl-4-Amine is a high-purity, fluorinated aromatic amine building block of significant importance in advanced organic synthesis. Its bifunctional structure, featuring both an amine group and a difluorinated biphenyl core, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, where the fluorine atoms enhance biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated components in liquid crystal displays (LCDs), improving dielectric anisotropy and thermal stability.
• Organic Electronic Materials: Employed in the research and production of organic semiconductors and charge-transport materials for OLEDs and other devices.
• Advanced Polymer Chemistry: Acts as a monomer or cross-linking agent for creating high-performance, specialty polymers with enhanced chemical resistance.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and material science research, enabling structure-activity relationship (SAR) studies.

Basic Information

Product Name	2',4'-Difluoro-Biphenyl-4-Amine
CAS No.	62575-36-4
Molecular Formula	C12H9F2N
Molecular Weight	205.21 g/mol
Synonyms	4-Amino-2',4'-difluorobiphenyl; [1,1'-Biphenyl]-4-amine, 2',4'-difluoro-; 2',4'-Difluoro-4-biphenylamine; 2,4'-Difluorobiphenyl-4-ylamine; 4-Biphenylamine, 2',4'-difluoro-; 2',4'-Difluoro[1,1'-biphenyl]-4-amine
EINECS	Contact for details

Quality Control

Our 2',4'-Difluoro-Biphenyl-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.