Description

4,6-Dimethyl-1H-Pyrimidine-2-Thione Hydrochloride is a versatile heterocyclic building block and key intermediate in organic synthesis. This compound matters for its role as a crucial precursor in the development of pharmaceuticals, agrochemicals, and advanced materials. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for synthesizing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of various drug candidates, particularly those with pyrimidine-based cores, such as kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the thiopyrimidine moiety is essential for biological activity.
• Organic Synthesis Building Block: Serves as a versatile precursor for constructing complex heterocyclic systems in medicinal and process chemistry.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities.
• Material Science Precursor: Potential use in the synthesis of organic ligands for metal-organic frameworks (MOFs) or functional polymers.

Basic Information

Product Name	4,6-Dimethyl-1H-Pyrimidine-2-Thione Hydrochloride
CAS No.	62501-45-5
Molecular Formula	C6H9N2S·HCl
Molecular Weight	176.67 g/mol
Synonyms	4,6-Dimethyl-2-mercaptopyrimidine hydrochloride; 2-Mercapto-4,6-dimethylpyrimidine hydrochloride; 4,6-Dimethyl-2-pyrimidinethiol hydrochloride; 4,6-Dimethyl-2-thiopyrimidine hydrochloride; 2-Thio-4,6-dimethylpyrimidine hydrochloride; NSC 403697; 4,6-Dimethylpyrimidine-2-thiol hydrochloride
EINECS	Contact for details

Quality Control

Our 4,6-Dimethyl-1H-Pyrimidine-2-Thione Hydrochloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be kept under dry conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.