Description

3-Amino-2-Chlorobenzotrifluoride is a versatile halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both amino and trifluoromethyl groups ortho to a chlorine atom, provides unique reactivity and physicochemical properties essential for creating high-value compounds. This intermediate is particularly valuable for manufacturers in the agrochemical and pharmaceutical sectors seeking to develop novel active ingredients with enhanced efficacy and patent life.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern herbicides, fungicides, and insecticides, where the trifluoromethyl group improves biological activity and environmental stability.
• Pharmaceutical Building Block: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Dye and Pigment Synthesis: Employed in the production of specialized dyes and pigments, where the amino group allows for diazotization and coupling reactions to create complex colorants.
• Liquid Crystal and Electronic Materials: Functions as a starting material for synthesizing fluorinated compounds used in liquid crystal displays (LCDs) and other electronic applications.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) to construct complex biaryl amines.

Basic Information

Product Name	3-Amino-2-Chlorobenzotrifluoride
CAS No.	62476-58-8
Molecular Formula	C7H5ClF3N
Molecular Weight	195.57 g/mol
Synonyms	2-Chloro-3-aminobenzotrifluoride; 2-Chloro-α,α,α-trifluoro-m-toluidine; 3-Amino-2-chloro-α,α,α-trifluorotoluene; 2-Chloro-3-(trifluoromethyl)aniline; 3-Amino-2-chlorobenzylidene trifluoride; 2-Chloro-α,α,α-trifluoro-3-methylaniline; m-Amino-o-chlorobenzotrifluoride; Benzenamine, 2-chloro-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3-Amino-2-Chlorobenzotrifluoride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for fine chemical synthesis. A Certificate of Analysis (COA) detailing all test results is provided with each shipment, guaranteeing traceability and consistent quality for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.