Description

7-Benzyl-5,6,7,8-Tetrahydro-3H-Pyrido[3,4-D]Pyrimidin-4-One Hydrochloride is a high-purity, pharmaceutically relevant heterocyclic compound, serving as a critical intermediate in modern drug discovery and development. Its value lies in its role as a versatile building block for synthesizing complex molecules targeting a range of therapeutic areas. This compound is primarily needed by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Chemical Biology Research: Used as a scaffold or probe in medicinal chemistry for structure-activity relationship (SAR) studies and target identification.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) campaigns.
• Process Chemistry Development: Serves as a starting material for optimizing scalable synthetic routes for potential APIs under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Utilized in university and institutional labs for methodological development and the study of heterocyclic chemistry.
• Contract Research & Manufacturing (CRAM): Supplied to service organizations supporting the pharmaceutical industry with custom synthesis and scale-up.

Basic Information

Product Name	7-Benzyl-5,6,7,8-Tetrahydro-3H-Pyrido[3,4-D]Pyrimidin-4-One Hydrochloride
CAS No.	62458-96-2
Molecular Formula	C₁₅H₁₇N₃O·HCl
Molecular Weight	291.78 g/mol
Synonyms	7-Benzyl-4-oxo-3,4,5,6,7,8-hexahydro-3H-pyrido[3,4-d]pyrimidine hydrochloride; 7-Benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidin-4-one HCl; 7-Benzyl-4-hydroxy-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidine hydrochloride; 62458-96-2; Pyrido[3,4-d]pyrimidin-4(3H)-one, 7-benzyl-5,6,7,8-tetrahydro-, hydrochloride; 7-Benzyl-4-oxo-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidine hydrochloride
EINECS	Contact for details

Quality Control

Our 7-Benzyl-5,6,7,8-Tetrahydro-3H-Pyrido[3,4-D]Pyrimidin-4-One Hydrochloride is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry for identity confirmation and purity assessment. Certificates of Analysis (COA) detailing specific lot results are available upon request, and we can support development toward cGMP standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.