Description

Glucagon (1-37) (Porcine) is a high-purity, 37-amino acid polypeptide fragment of the porcine glucagon hormone. This specific peptide sequence is a critical reference standard and research tool for studying glucagon's structure, function, and receptor interactions. It is essential for pharmaceutical R&D, academic research, and diagnostic development. Key users include biotech companies, contract research organizations (CROs), and university laboratories focused on endocrinology, diabetes research, and metabolic disorder therapeutics.

Application

• Pharmaceutical Reference Standard: Used for the calibration and validation of analytical methods (HPLC, MS) in drug development and quality control.
• Biochemical Research: Serves as a key reagent in studies investigating glucagon's physiological mechanisms, receptor binding affinity, and signal transduction pathways.
• Antibody Production & Immunoassay Development: Acts as an immunogen for generating specific antibodies or as a calibrator in ELISA and RIA kits for glucagon detection.
• Metabolic Disease Studies: Utilized in in vitro and in vivo models to explore the role of glucagon in diabetes, obesity, and other metabolic syndromes.
• Peptide Chemistry & Synthesis: Employed as a benchmark compound for comparing synthetic glucagon analogs and studying structure-activity relationships (SAR).
• Cell Signaling & Molecular Biology: Applied in cell-based assays to study cAMP production and other downstream effects of glucagon receptor activation.

Basic Information

Product Name	Glucagon (1-37) (Porcine)
CAS No.	62340-29-8
Molecular Formula	C₁₅₃H₂₂₅N₄₃O₄₉S
Molecular Weight	3482.8 g/mol
Synonyms	Porcine Glucagon (1-37); Glucagon 1-37, porcine; H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH; Glucagon Fragment 1-37 (Porcine); Glucagon (swine); Glucagon, porcine (1-37); Glucagon porcine fragment 1-37
EINECS	Contact for details

Quality Control

Our Glucagon (1-37) (Porcine) is manufactured under strict controls to ensure the highest standards of purity and consistency, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), peptide content, amino acid analysis, and other critical parameters. We adhere to cGMP guidelines for the production of peptide reference materials to guarantee reliable and reproducible performance in your assays.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with theoretical molecular weight
Purity (HPLC)	≥ 95.0%
Peptide Content (UV)	≥ 80.0%
Amino Acid Analysis	Within ±10% of theoretical composition
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.