Description

n-α-Z-n-β-Boc-D-2,3-Diaminopropionic Acid is a sophisticated, orthogonally protected derivative of the non-proteinogenic amino acid 2,3-diaminopropionic acid (Dap). This compound is engineered to provide selective deprotection pathways, making it a critical building block for the synthesis of complex peptides and peptidomimetics. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, particularly for developing novel antibiotics, enzyme inhibitors, and targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Serves as a specialized, protected amino acid for solid-phase and solution-phase peptide synthesis, enabling the incorporation of the Dap scaffold.
• Antibiotic Research: Used in the construction of peptide-based antibiotics that target bacterial cell wall synthesis.
• Chemical Biology Probes: Employed to create labeled or modified peptides for studying protein-protein interactions and enzyme mechanisms.
• Linker & Conjugation Chemistry: The dual amino functionality allows it to act as a versatile linker for bioconjugation and drug-antibody conjugate (ADC) development.
• Material Science: Potential use in creating novel polymeric materials with specific functional groups derived from its structure.

Basic Information

Product Name	n-α-Z-n-β-Boc-D-2,3-Diaminopropionic Acid
CAS No.	62234-36-0
Molecular Formula	C₁₇H₂₄N₂O₆
Molecular Weight	352.38 g/mol
Synonyms	D-2,3-Diaminopropionic Acid, Nα-Z-Nβ-Boc derivative; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-((tert-butoxycarbonyl)amino)propanoic Acid; Boc-D-Dap(Z)-OH; Fmoc-D-Dap(Boc)-OH; Nα-(9-Fluorenylmethyloxycarbonyl)-Nβ-(tert-butoxycarbonyl)-D-2,3-diaminopropionic Acid; Z-D-Dap(Boc)-OH; N-Z-N'-Boc-D-2,3-diaminopropanoic Acid
EINECS	Contact for details

Quality Control

Every batch of n-α-Z-n-β-Boc-D-2,3-Diaminopropionic Acid is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.