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Calcium Sennoside CAS NO 62211-03-4
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CAS No.:62211-03-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Calcium Sennoside is a purified, standardized mixture of the calcium salts of sennosides A and B, derived from senna leaves. This active pharmaceutical ingredient (API) is valued for its reliable and predictable stimulant laxative effect, making it a critical component in pharmaceutical formulations. It is primarily used by manufacturers in the pharmaceutical and nutraceutical industries for producing over-the-counter and prescription laxative products, tablets, and capsules.
Application
- Pharmaceutical API: Primary active ingredient in prescription and OTC stimulant laxative medications.
- Tablet & Capsule Formulation: Used in solid oral dosage forms for the treatment of occasional constipation.
- Bowel Evacuation Preparations: Key component in formulations used for colon cleansing prior to diagnostic procedures like colonoscopy.
- Herbal & Nutraceutical Extracts: Standardized ingredient in herbal supplements and natural health products targeting digestive health.
- Veterinary Pharmaceuticals: Employed in veterinary medicine for animal laxative treatments.
- Clinical Research: Used as a reference standard or active compound in pharmacological and clinical studies.
Basic Information
| Product Name | Calcium Sennoside |
| CAS No. | 62211-03-4 |
| Molecular Formula | C₂₉H₂₆CaO₁₄ (for Sennoside A calcium salt) |
| Molecular Weight | 862.8 g/mol (for Sennoside A calcium salt) |
| Synonyms | Sennosides Calcium; Calcium Sennosides; Sennoside A and B Calcium Salt; Senna Extract Calcium Salt; CAS 62211-03-4; Sennosides A and B, calcium salts; Sennosides (Calcium Complex) |
| EINECS | Contact for details |
Quality Control
Our Calcium Sennoside is manufactured under strict quality management systems. Each batch is tested to ensure it meets stringent specifications for identity, purity, and potency, aligning with pharmacopeial standards. A comprehensive Certificate of Analysis (COA) detailing assay, related substances, and microbiological quality is provided with every shipment to guarantee traceability and compliance.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.
Specification
| Item | Specification |
|---|---|
| Appearance | Yellowish-brown to brown, fine powder |
| Identification (IR) | Conforms to standard |
| Identification (HPLC) | Conforms to standard |
| Assay (HPLC) | NLT 90.0% of total sennosides (calculated as Sennoside B) |
| Sennoside A | Contact for details |
| Sennoside B | Contact for details |
| Loss on Drying | NMT 8.0% |
| Residue on Ignition | Contact for details |
| Heavy Metals | NMT 20 ppm |
| Microbiological Control | Meets Ph. Eur./USP requirements |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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