Description

4-Fluoro-n-(2,2,2-Trifluoroethyl)Aniline is a specialized fluorinated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both aromatic fluorine and a trifluoroethylamine side chain, makes it a valuable intermediate for creating compounds with enhanced biological activity and specific physicochemical properties. This high-purity intermediate is essential for research and development in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides that require fluorinated motifs for improved efficacy and environmental profile.
• Liquid Crystal & Electronic Materials: Used in the production of fluorinated components for liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Serves as a monomer or modifier in the synthesis of specialty polymers, such as polyimides and fluoropolymers, for high-performance applications.
• Dye & Pigment Manufacturing: Intermediate for creating fluorinated dyes and pigments that offer superior lightfastness and color stability.
• Research & Development: A versatile scaffold in medicinal and material science research for structure-activity relationship (SAR) studies and novel compound libraries.

Basic Information

Product Name	4-Fluoro-n-(2,2,2-Trifluoroethyl)Aniline
CAS No.	62158-94-5
Molecular Formula	C8H7F4N
Molecular Weight	193.14 g/mol
Synonyms	N-(2,2,2-Trifluoroethyl)-4-fluoroaniline; 4-Fluoro-N-(2,2,2-trifluoroethyl)benzenamine; 1-Fluoro-4-[(2,2,2-trifluoroethyl)amino]benzene; 4-Fluoro-N-(trifluoroethyl)aniline; 4-Fluoro-alpha,alpha,α-trifluoro-N-ethylaniline; p-Fluoro-N-(2,2,2-trifluoroethyl)aniline; Benzenamine, 4-fluoro-N-(2,2,2-trifluoroethyl)-
EINECS	Contact for details

Quality Control

Our 4-Fluoro-n-(2,2,2-Trifluoroethyl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.