Description

2-(2,2,2-Trifluoroethoxy)Aniline is a specialized aromatic amine derivative featuring a trifluoroethoxy substituent, a key intermediate in advanced organic synthesis. This compound is valued for its unique combination of an aniline moiety and a fluorinated ether group, which imparts distinct electronic and lipophilic properties to target molecules. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity, metabolic stability, and environmental persistence.
• Liquid Crystal & Electronic Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), improving dielectric anisotropy and thermal stability.
• Polymer & Material Science: Employed as a monomer or modifier in the synthesis of specialty polymers, coatings, and resins to introduce fluorine for enhanced chemical resistance, lower surface energy, and improved weatherability.
• Dye & Pigment Intermediate: Acts as a key starting material for synthesizing novel fluorinated dyes and pigments, offering improved color fastness and solubility properties.

Basic Information

Product Name	2-(2,2,2-Trifluoroethoxy)Aniline
CAS No.	62149-83-1
Molecular Formula	C8H8F3NO
Molecular Weight	191.15 g/mol
Synonyms	2-Amino-1-(2,2,2-trifluoroethoxy)benzene; 1-Amino-2-(2,2,2-trifluoroethoxy)benzene; 2-(2,2,2-Trifluoroethoxy)benzenamine; 2-Trifluoroethoxyaniline; o-(Trifluoroethoxy)aniline; Benzenamine, 2-(2,2,2-trifluoroethoxy)-; 2-TFEA
EINECS	Contact for details

Quality Control

Our 2-(2,2,2-Trifluoroethoxy)Aniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP standards where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.