Description

Carbamic Acid, (7-Aminoheptyl)-, 1,1-Dimethylethyl Ester, Monohydrochloride is a protected amino acid derivative, specifically a Boc-protected heptanediamine hydrochloride salt, which serves as a critical building block in organic synthesis. Its primary value lies in providing a reactive primary amine group that is temporarily shielded, enabling precise, sequential coupling in the construction of complex molecules like peptides, peptidomimetics, and other bioactive compounds. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require reliable and scalable synthetic precursors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in peptide-based drug discovery and development.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to introduce a C7 aliphatic spacer with a protected amine functionality.
• Bioconjugation & Linker Chemistry: Serves as a versatile linker or spacer arm for conjugating drugs, dyes, or other molecules to proteins, antibodies, or nanoparticles.
• Polymer & Dendrimer Synthesis: A monomer for creating functionalized polymers, dendrimers, and hydrogels with amine groups for further modification.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and inhibitors for studying biological pathways.
• Agrochemical Research: Intermediate in the development of novel crop protection agents and plant growth regulators.

Basic Information

Product Name	Carbamic Acid, (7-Aminoheptyl)-, 1,1-Dimethylethyl Ester, Monohydrochloride
CAS No.	62146-57-0
Molecular Formula	C₁₂H₂₆N₂O₂·HCl
Molecular Weight	266.81 g/mol
Synonyms	7-[(tert-Butoxycarbonyl)amino]heptylamine hydrochloride; 1,1-Dimethylethyl N-(7-aminoheptyl)carbamate hydrochloride; N-Boc-1,7-diaminoheptane hydrochloride; Nα-Boc-1,7-diaminoheptane hydrochloride; Boc-DAH.HCl; tert-Butyl (7-aminoheptyl)carbamate hydrochloride; N-(7-Aminoheptyl)carbamic acid tert-butyl ester hydrochloride; Boc-7-aminoheptylamine hydrochloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity synthetic intermediates. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific test results are available upon request. We support cGMP manufacturing requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.